EDCtox

Mechanistic evidence atlas. Scores summarise biological direction and magnitude. They are not a toxicity rank or a human-risk number.

Compare

Two to six compounds, domain by domain. A higher number in one column is not added to another column. Unscored analogues are left blank rather than copied from a parent chemical.

BPA, BPAF, BPSDEHP, DINP, DINCHOlanzapine, risperidone, aripiprazoleFluoxetine, sertraline, methylphenidatePFOS, PFOAParaquat, rotenone, boscalidMelatonin, paraquat, rotenone
DomainOlanzapineRisperidoneAripiprazole
REP
Reproductive
+2
H3 · substantial human observation plus biology · Moderate
+4
H4 · established at relevant human exposure · High
—
No headline
DEV
Developmental
+2
H1 · mechanistic, cellular, or high-dose animal · Low
+3
H2 · strong experimental, limited human · Low
—
No headline
NEUROENDO
Neuroendocrine / HPA
+3
H4 · established at relevant human exposure · High
+4
H4 · established at relevant human exposure · High
—
No headline
IMM
Immune
—
No headline
—
No headline
—
No headline
MET
Metabolic
+4
H4 · established at relevant human exposure · High
+3
H3 · substantial human observation plus biology · Moderate
—
No headline
MITO
Mitochondrial
+3
H1 · mechanistic, cellular, or high-dose animal · Low
—
No headline
—
No headline
REDOX
Redox
+3
H1 · mechanistic, cellular, or high-dose animal · Low
—
No headline
—
No headline