protects against Melatonin
Experimental reports of reduced oxidative and mitochondrial neuronal injury. Not a demonstrated clinical antidote.
Paraquat
Paraquat
- Category
- herbicide · Bipyridyl herbicide
- Record
- specific compound · restricted
- Identifiers
- CAS 4685-14-7 · C12H14N2
- Aliases
- Paraquat dichloride
Bipyridyl herbicide. Seed assessments emphasise mitochondrial and redox activity. Classical estrogen or androgen receptor activity is not scored.
CAS is the cation. Formulations commonly use the dichloride (CAS 1910-42-5). Status is jurisdiction-dependent.
Flags: environmental chemical
Phase-1 numbers are seed hypotheses. They are not curated consensus, not a toxicity total, and not a statement of human risk. Association is not written as causation.
protects against Melatonin · -3
Experimental models report less oxidative and mitochondrial neuronal injury when melatonin is present with paraquat. This is not demonstrated clinical benefit.
Animal and cellular protection does not establish a treatment effect in humans. Dose, timing, and formulation are not curated.
LOW confidence · H1. Experimental protection is not clinical benefit. · Brain · Dopaminergic neuron · Experimental models under toxicant or oxidative stress