EDCtox

Mechanistic evidence atlas. Scores summarise biological direction and magnitude. They are not a toxicity rank or a human-risk number.

Compounds

Zidovudine (representative older NRTI)

Zidovudine

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Category
pharmaceutical · Nucleoside reverse transcriptase inhibitor
Record
representative stand in · in current use
Identifiers
CAS 30516-87-1
Aliases
AZT

Named stand-in for an older nucleoside reverse transcriptase inhibitor, a class with mitochondrial toxicity concerns. No score is assigned in this phase.

Mitochondrial toxicity of older NRTIs is a class question. This row is zidovudine only.

Flags: pharmaceutical

Phase-1 numbers are seed hypotheses. They are not curated consensus, not a toxicity total, and not a statement of human risk. Association is not written as causation.

No findings are linked. The publication, when one exists, is not itself the scored unit.