ER-alpha agonism
ER_ALPHA_AGONISM
Estrogen receptor alpha agonism or activation. A binding or reporter result is not itself a human disease claim.
No claims yet. The supporting sentence stays unlisted. Claim count does not change a score.
Identity
- Domain
- REP · Reproductive endocrinology
- Family
- No family
- Aggregation group
- ESTROGEN_RECEPTOR
- Score policy
- scorable
Hierarchy
Parent: Estrogen receptor axis
No child mechanisms.
Siblings: ER-alpha antagonism, ER-beta agonism, ER-beta antagonism, GPER signalling
External mappings
No external mapping is stored.
Assessments
These are synthesized judgments. They are separate from the claims below, and the claim count does not set the score.
- BPA+4
Disruptive signal · Moderate confidence · H3 · substantial human observation plus biology · seed hypothesis
- Fluoxetine+3
Context-dependent · Low confidence · H1 · mechanistic, cellular, or high-dose animal · seed hypothesis
- Paraquatnot quantified
Direction uncertain · Low confidence · H0 · no meaningful human evidence · seed hypothesis
- TFAnot quantified
Direction uncertain · Low confidence · H0 · no meaningful human evidence · seed hypothesis
Claims
- Claims
- 0
- Papers
- 0
- Curator verified
- 0
- Candidate mappings
- 0
- Directness:
- None recorded
- Species:
- None recorded
- Tissue:
- None recorded
- Cell:
- None recorded
No claims yet.