3β-HSD
HSD3B
3β-HSD. Mechanism node for evidence linkage. A row here is not itself a finding.
Candidate mappings only. No curator-verified mapping yet. The supporting sentence stays unlisted. Claim count does not change a score.
Identity
- Domain
- REP · Reproductive endocrinology
- Family
- No family
- Aggregation group
- STEROIDOGENESIS
- Score policy
- scorable
Hierarchy
Parent: Steroidogenic enzymes
No child mechanisms.
Siblings: Progesterone receptor, Aromatase (CYP19A1), StAR, CYP11A1, CYP17A1, 17β-HSD, Testosterone, Estradiol, Progesterone
External mappings
No external mapping is stored.
Assessments
These are synthesized judgments. They are separate from the claims below, and the claim count does not set the score.
No assessment is stored. That is not evidence of no activity.
Claims
- Claims
- 2
- Papers
- 2
- Curator verified
- 0
- Candidate mappings
- 2
- Directness:
- INFERRED 1 · STRONGLY_SUPPORTED 1
- Species:
- human 2
- Tissue:
- ovary 2
- Cell:
- granulosa 2 · theca 1
| Claim | Paper | Context | Directness | Mapping |
|---|---|---|---|---|
| BPAbisphenol A increases expression 3β-HSD | Bisphenol a Disrupts Steroidogenesis and Induces Apoptosis in Human Granulosa Cells Cultured In Vitro.2025 · PMID 40362320 · DOI · Abstract | human · ovary · granulosa · 0.001 µM, 0.1 µM, 100 µM | strongly supportedhigh confidence | candidateMachine-extracted |
| BPAbisphenol A impairs function 3β-HSDReview-derived | Bisphenol A and ovarian steroidogenesis.2016 · PMID 27543890 · DOI · Abstract | human · ovary · granulosa; theca | inferredmoderate confidence | candidateMachine-extracted |