EDCtox

Mechanistic evidence atlas. Scores summarise biological direction and magnitude. They are not a toxicity rank or a human-risk number.

Compounds

Fluopyram

Fluopyram

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Category
fungicide · SDHI fungicide
Record
specific compound · unknown
Identifiers
CAS 658066-35-4
Aliases
—

SDHI fungicide. Complex II relevance is a shared mode-of-action hypothesis, not a curated compound-specific human assessment.

Flags: environmental chemical

Phase-1 numbers are seed hypotheses. They are not curated consensus, not a toxicity total, and not a statement of human risk. Association is not written as causation.
REP
Reproductive
—
DEV
Developmental
—
NEUROENDO
Neuroendocrine / HPA
—
IMM
Immune
—
MET
Metabolic
—
MITO
Mitochondrial
+4
REDOX
Redox
—

Left of the centre line is protective or restorative. Right is disruptive. Physiological activity is labelled and is not drawn as disruption. Domains are not added together.

REP · Reproductive

—

No quantitative mechanistic score is stored for this domain.

Direction: Direction uncertain
Confidence: —
Human relevance: —
Findings 0 supporting / 0 contradictory · 0 capped

DEV · Developmental

—

No quantitative mechanistic score is stored for this domain.

Direction: Direction uncertain
Confidence: —
Human relevance: —
Findings 0 supporting / 0 contradictory · 0 capped

NEUROENDO · Neuroendocrine / HPA

—

No quantitative mechanistic score is stored for this domain.

Direction: Direction uncertain
Confidence: —
Human relevance: —
Findings 0 supporting / 0 contradictory · 0 capped

IMM · Immune

—

No quantitative mechanistic score is stored for this domain.

Direction: Direction uncertain
Confidence: —
Human relevance: —
Findings 0 supporting / 0 contradictory · 0 capped

MET · Metabolic

—

No quantitative mechanistic score is stored for this domain.

Direction: Direction uncertain
Confidence: —
Human relevance: —
Findings 0 supporting / 0 contradictory · 0 capped

MITO · Mitochondrial

+4

Headline +4 is the strongest independent cluster (ETC_COMPLEX_II: ETC complex II). Other clusters and child mechanisms were not added. Human relevance is the relevance of the headline cluster, not the maximum relevance anywhere in the domain, and it is not multiplied into the score. No curated scientific findings are linked yet. The number is a seed assessment, not a literature count. Direction DISRUPTIVE. Confidence MODERATE. Human relevance H1. Supporting findings 0. Contradictory findings 0. Curation SEED_HYPOTHESIS.

Direction: Disruptive signal
Confidence: Moderate
Human relevance: H1 · mechanistic, cellular, or high-dose animal
Findings 0 supporting / 0 contradictory · 0 capped

REDOX · Redox

—

No quantitative mechanistic score is stored for this domain.

Direction: Direction uncertain
Confidence: —
Human relevance: —
Findings 0 supporting / 0 contradictory · 0 capped