EDCtox

Mechanistic evidence atlas. Scores summarise biological direction and magnitude. They are not a toxicity rank or a human-risk number.

Compounds

Methylphenidate

Methylphenidate

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Category
pharmaceutical · Stimulant
Record
specific compound · in current use
Identifiers
CAS 113-45-1
Aliases
MPH

Stimulant. Appetite and growth effects at therapeutic doses are recorded separately from experimental mitochondrial findings, whose relevance at therapeutic human doses is uncertain.

Flags: pharmaceutical

Phase-1 numbers are seed hypotheses. They are not curated consensus, not a toxicity total, and not a statement of human risk. Association is not written as causation.

Reduced appetite +3 · H4 · high

Reduced appetite at therapeutic doses is a clinical effect. It does not demonstrate neuronal mitochondrial injury.

Phase-1 seed hypothesis, not a curated systematic review. Where a range was discussed, the stored integer is the conservative end closer to zero. A score is biological direction and magnitude, not human risk.

Reduced linear growth +2 · H3 · moderate

Slower height gain during treatment is recorded separately from experimental mitochondrial scores.

Phase-1 seed hypothesis, not a curated systematic review. Where a range was discussed, the stored integer is the conservative end closer to zero. A score is biological direction and magnitude, not human risk.