EDCtox

Mechanistic evidence atlas. Scores summarise biological direction and magnitude. They are not a toxicity rank or a human-risk number.

Compounds

Olanzapine

Olanzapine

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Category
pharmaceutical · Atypical antipsychotic
Record
specific compound · in current use
Identifiers
CAS 132539-06-1
Aliases
—

Atypical antipsychotic. Metabolic disruption at therapeutic doses is recorded separately from dopamine pharmacology and from mitochondrial hypotheses.

Flags: pharmaceutical

Phase-1 numbers are seed hypotheses. They are not curated consensus, not a toxicity total, and not a statement of human risk. Association is not written as causation.

Insulin resistance +4 · H4 · high

Clinical association with insulin resistance during therapeutic use. This outcome is not inferred solely from the IRS1 mechanism row.

Phase-1 seed hypothesis, not a curated systematic review. Where a range was discussed, the stored integer is the conservative end closer to zero. A score is biological direction and magnitude, not human risk.

Weight gain +4 · H4 · high

Weight gain is an established treatment-associated outcome. It is not the same measurement as a mitochondrial assay.

Phase-1 seed hypothesis, not a curated systematic review. Where a range was discussed, the stored integer is the conservative end closer to zero. A score is biological direction and magnitude, not human risk.