EDCtox

Mechanistic evidence atlas. Scores summarise biological direction and magnitude. They are not a toxicity rank or a human-risk number.

Compounds

Valproate

Valproic acid

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Category
pharmaceutical · Antiseizure medication
Record
specific compound · in current use
Identifiers
CAS 99-66-1
Aliases
Sodium valproate, Valproic acid

Antiseizure medication. Developmental toxicity is established and is largely not specifically endocrine. Metabolic and mitochondrial signals are recorded separately.

Flags: pharmaceutical

Phase-1 numbers are seed hypotheses. They are not curated consensus, not a toxicity total, and not a statement of human risk. Association is not written as causation.

Neurodevelopmental change +4 · H4 · high

Neurodevelopmental and neural-tube harm after gestational exposure is established. Much of that harm is not specifically endocrine.

Phase-1 seed hypothesis, not a curated systematic review. Where a range was discussed, the stored integer is the conservative end closer to zero. A score is biological direction and magnitude, not human risk.