Melatonin
Melatonin
- Category
- hormone · Endogenous hormone / pharmaceutical
- Record
- specific compound · in current use
- Identifiers
- CAS 73-31-4 · C13H16N2O2
- Aliases
- 5-methoxy-N-acetyltryptamine, N-acetyl-5-methoxytryptamine
Endogenous pineal hormone and a pharmaceutical used for sleep. High MT1/MT2 activity is physiological. Developmental reproductive effects of long-term childhood use are not established in this seed.
Flags: pharmaceutical · endogenous
Phase-1 numbers are seed hypotheses. They are not curated consensus, not a toxicity total, and not a statement of human risk. Association is not written as causation.
| Context | Life stage | Type | Dose metric | Real-world relevance |
|---|---|---|---|---|
Children using exogenous melatonin Long-term childhood use. Puberty effects are a data gap. | childhood | therapeutic | prescribed dose | uncertain |
Experimental models under toxicant or oxidative stress Co-exposure or pretreatment models. Not a clinical regimen and not evidence of clinical benefit. | adult | experimental | administered dose | low |
Adults using exogenous melatonin Exogenous sleep use. Not the same as endogenous nocturnal secretion. | adult | therapeutic | prescribed dose | moderate |